Disturbed intracellular folate homeostasis impairs autophagic flux and increases hepatocytic lipid accumulation

Abstract Background Metabolic associated fatty liver disease (MAFLD), a prevalent liver disorder affecting one-third of the global population, encompasses a spectrum ranging from fatty liver to severe hepatic steatosis.Both genetic and lifestyle factors, particularly diet and nutrition, contribute to its etiology.Folate deficiency, a frequently enc

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Oral immunotherapy for peanut allergy: The con argument

Background: In some countries of the world, peanut allergy represents an important source of anaphylactic reactions.Traditionally treated with the avoidance of responsible allergens, this condition can also be targeted by oral peanut immunotherapy.Methods: In this study, we review the beneficial and side effects of currently available forms of pean

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Technetium-99m-labeled deoxynivalenol from Fusarium mycotoxin alters organ toxicity in BALB/c mice by oral and intravenous route

The Ceramic Plant Pot toxicity of deoxynivalenol, both intravenously and orally, was investigated in male and female BALB/c mice.Technetium-99m (99m Tc)-labeled deoxynivalenol was administered to mice by tail vein injection and orally dosed.Distribution of labeled deoxynivalenol at 26 hours was monitored by gamma-scintigraphy.In the evaluated organ

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